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Updated: Aug 9, 2026

Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy
Published on: June 8, 2018
Replicative and repair DNA synthesis after solar damage
Abstract:
It is possible to enhance the individually maximal spontaneous extent of unscheduled DNA synthesis after ultraviolet light damage in human skin by 40% using topical pretreatment with bifidus fraction compounds (7,8,9). This new and biological method of active radiation protection (4,5,7), has been shown to be unaffected by any artificially produced findings due to hydroxyurea, butyrates of misinterpreted thymidine labels from replicative SDS and repair UDS. The original experimental results could be reproduced also by others, even using completely different test methods. Obviously, the results are dependent on an appropriate topical compound allowing sufficient release and penetration.
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Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...

