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Colloids

Colloids

Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...

Bioavailability Enhancement: Drug Permeability Enhancement

Bioavailability Enhancement: Drug Permeability Enhancement

Body:After oral administration, poor permeability often limits the rate at which drugs are absorbed through the intestinal epithelium. Enhancing drug permeability is crucial for effective therapy, and several strategies have been developed to overcome this challenge.One effective strategy involves the use of lipid-based formulations. These formulations enhance dissolution and solubility, targeting physiological mechanisms to increase drug absorption. This includes stimulating bile salt...

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

Body:Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...

Colloids and Suspensions

Colloids and Suspensions

Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles visible to the naked eye or seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. The suspended particles in a suspension settle out after some time of mixing. The separation of particles from a suspension is...

Drug Delivery: Overview

Drug Delivery: Overview

The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...

Bioavailability Enhancement: Determination and Conceptual Approaches in Overcoming Bioavailability Problems

Bioavailability Enhancement: Determination and Conceptual Approaches in Overcoming Bioavailability Problems

Body:Bioavailability is a critical pharmacological concept that measures the extent and rate at which an active drug ingredient or therapeutic moiety enters the systemic circulation, remaining unchanged. It's a pivotal factor in determining a drug's efficacy and safety.The Biopharmaceutics Classification System (BCS) plays an essential role in drug development by categorizing drugs into four classes based on their solubility and permeability. This classification aids in understanding drug...

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Related Experiment Video

Updated: Oct 12, 2025

Formulation and Characterization of Bioactive Agent Containing Nanodisks

Formulation and Characterization of Bioactive Agent Containing Nanodisks

Published on: March 17, 2023

Plant-Based Colloidal Delivery Systems for Bioactives.

Yunbing Tan¹, David Julian McClements^1,2

¹Department of Food Science, University of Massachusetts Amherst, Amherst, MA 01003, USA.

Molecules (Basel, Switzerland)

|November 27, 2021

Summary

This summary is machine-generated.

Plant-based colloidal systems enhance bioactive delivery in foods. These systems, made from botanical ingredients, improve nutrient stability and bioavailability for healthier plant-based products.

Keywords:

bioactives colloidal systems emulsions functionality plant-based delivery

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Area of Science:

Food Science
Colloid Science
Nutritional Science

Background:

Supplementing plant-based foods with bioactive agents can enhance human health.
Colloidal delivery systems improve the dispersibility, stability, and bioavailability of bioactives.
Plant-based delivery systems offer a sustainable approach to encapsulating functional ingredients.

Purpose of the Study:

To review colloidal delivery systems made entirely from plant-based ingredients.
To highlight the encapsulation, protection, and release of various bioactives using these systems.
To discuss the potential applications of plant-based delivery systems in food analogs.

Main Methods:

Focus on colloidal systems assembled from plant-derived lipids, proteins, polysaccharides, phospholipids, and surfactants.
Cover the creation of plant-based nanoemulsions, nanoliposomes, nanoparticles, and microgels.
Discuss tailoring system functionality through ingredient selection and processing.

Main Results:

Plant-based delivery systems can encapsulate diverse bioactives, including vitamins, omega-3 oils, carotenoids, curcuminoids, and polyphenols.
System functionality is controllable by adjusting composition, size, shape, internal structure, surface chemistry, and electrical properties.
These systems show promise for incorporation into plant-based food, meat, seafood, milk, and egg alternatives.

Conclusions:

Plant-based colloidal systems offer a versatile platform for delivering bioactive agents in functional foods.
Further research is needed to compare the performance of different delivery systems for specific applications.
In vivo studies are required to validate the efficacy of these systems in delivering bioavailable bioactives.