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COVID-19: Update on Its Ocular Involvements, and Complications From Its Treatments and Vaccinations
Timothy P H Lin1, Chung-Nga Ko2, Ke Zheng3
1Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.
Insights
This review covers how coronavirus disease 2019 (COVID-19) affects the eyes, including ocular complications and treatment side effects. It aims to guide ophthalmologists in managing eye conditions during the ongoing pandemic.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Public Health
Background:
- The COVID-19 pandemic, caused by SARS-CoV-2, has significantly impacted global health.
- Ophthalmologists face risks of SARS-CoV-2 exposure due to patient proximity.
- SARS-CoV-2 exhibits ocular tropism, leading to eye complications.
Purpose of the Study:
- To review ophthalmic manifestations of COVID-19.
- To summarize the ocular effects of COVID-19 treatments and vaccines.
- To provide guidance for ophthalmic care during the pandemic.
Main Methods:
- Literature review of recent studies on COVID-19 and ophthalmology.
- Analysis of reported ocular complications and treatment effects.
- Synthesis of information on SARS-CoV-2 ocular tropism.
Main Results:
- Ophthalmologists are at high risk for SARS-CoV-2 infection.
- COVID-19 can cause various ocular complications.
- Therapeutic interventions and vaccinations may have adverse ocular effects.
Conclusions:
- Ophthalmic care requires awareness of COVID-19's ocular manifestations and treatment impacts.
- Further research is needed to fully understand long-term ocular consequences.
- Effective patient management necessitates an integrated approach to eye health and COVID-19.
Abstract:
The coronavirus disease 2019 (COVID-19) came under the attention of the international medical community when China first notified the World Health Organization of a pneumonia outbreak of then-unknown etiology in Wuhan in December 2019. Since then, COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has appalled the world by spreading at a pandemic speed. Although ophthalmologists do not directly engage in the clinical care of COVID-19 patients, the ophthalmology community has become aware of the close ties between its practice and the pandemic. Not only are ophthalmologists at heightened risk of SARS-CoV-2 exposure due to their physical proximity with patients in routine ophthalmic examinations, but SARS-CoV-2 possesses ocular tropism resulting in ocular complications beyond the respiratory tract after viral exposure. Furthermore, patients could potentially suffer from adverse ocular effects in the therapeutic process. This review summarized the latest literature to cover the ophthalmic manifestations, effects of treatments, and vaccinations on the eye to aid the frontline clinicians in providing effective ophthalmic care to COVID-19 patients as the pandemic continues to evolve.
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