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Updated: Oct 11, 2025

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Machine Learning for Ischemic Heart Disease Diagnosis Aided by Evolutionary Computing
Mohammad Alsaffar1, Abdullah Alshammari1, Gharbi Alshammari1
1University of Ha'il, College of Computer Science and Engineering, Department of Computer Science and Information, Saudi Arabia.
Abstract:
Heart disease is the leading cause of death from chronic diseases in the developing countries. The difficulty of making an accurate and timely diagnosis is exacerbated by a lack of resources and professionals in some areas, which contributes to this reality. Medical professionals may benefit from technological advancements that aid in the accurate diagnosis of patients. In light of these findings, a hybrid diagnostic tool has been developed that combines several computational intelligence (machine learning) techniques capable of analyzing clinical histories and images of electrocardiogram signals and indicating whether or not the patient has ischemic heart disease with up to 97.01% accuracy. Working with medical experts and a database containing clinical data on approximately 1020 patients and their diagnoses was required for this project. Both were put to use. A picture database containing 92 images of electrocardiogram signals was also used in this project for the analysis of the Artificial Neural Network. After extensive research and testing by the medical community, which supported the project and provided positive feedback, a successful tool was developed. This demonstrated the tool's effectiveness.
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