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Updated: Oct 11, 2025

Evaluation of Host-Pathogen Responses and Vaccine Efficacy in Mice
Published on: February 22, 2019
Host factors and vaccine efficacy: Implications for COVID-19 vaccines
Shahab Falahi1, Azra Kenarkoohi2
1Zoonotic Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Abstract:
The efficacy of the vaccines varies between individuals and populations. The immunogenicity of the vaccine is influenced by various factors, including host factors. Previous studies have shown that host factors affect the effectiveness of vaccines, which may be true about COVID-19 vaccines. In this review, we evaluate the possible association of host factors with vaccine efficacy with a special focus on COVID-19 vaccines.
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