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Trend of Antibiotic Use in Children with Acute Otitis Media in Korea

Kyu Hyun Park1, Seung-Ah Choe2, Ju-Young Shin3

  • 1Department of Pediatrics, Korea University Anam Hospital, Seoul, Korea.

Journal of Korean Medical Science
|November 30, 2021
PubMed

Insights

Antibiotic use for acute otitis media (AOM) in South Korean children increased for amoxicillin/amoxicillin-clavulanate but decreased for cephalosporin and macrolide from 2012-2018. A comprehensive strategy is needed to combat antimicrobial resistance.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Pharmacology

Background:

  • Public health interventions aim to optimize antibiotic use in pediatric acute otitis media (AOM).
  • Understanding antibiotic prescription patterns is crucial for antimicrobial stewardship.

Purpose of the Study:

  • To analyze trends in AOM-related antibiotic prescriptions among children in South Korea.
  • To identify changes in the use of specific antibiotic classes between 2012 and 2018.

Main Methods:

  • Utilized national Health Insurance Review & Assessment Service data.
  • Constructed a cohort of children aged 0-6 years diagnosed with AOM (2012-2018).
  • Analyzed prescription data for amoxicillin/amoxicillin-clavulanate, cephalosporins, and macrolides.

Main Results:

  • Antibiotic prescriptions for amoxicillin/amoxicillin-clavulanate increased from 56.1% (2012) to 61.8% (2018).
  • Prescriptions for cephalosporins decreased from 35.1% (2012) to 31.8% (2018).
  • Macrolide prescriptions declined from 8.7% (2012) to 6.4% (2018).

Conclusions:

  • AOM-related aminopenicillin prescriptions show an upward trend in South Korea.
  • Cephalosporin and macrolide use for AOM has decreased.
  • A multi-faceted approach is necessary for population-level antimicrobial resistance control.

Keywords:
AntibioticChildrenKoreaOtitis Media

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