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Studying Inherited Immunity in a Caenorhabditis elegans Model of Microsporidia Infection
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Helminths make themselves at home
1Department of Immunology, University of Washington, Seattle, WA.
The Journal of Experimental Medicine
|November 30, 2021
Abstract:
Drurey et al. (2021. J. Exp. Med.https://doi.org/10.1084/jem.20211140) show that excretory/secretory products from the parasitic helminth Heligmosomoides polygyrus suppress the host-protective small intestinal epithelial response. These findings establish that helminths directly modulate the tissue in which they live, shining new light on the host-parasite interaction.
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