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Capabilities of global high-level isolation units: A pre-workshop survey
Jocelyn J Herstein1, Timo Wolf2, Emanuele Nicastri3
1University of Nebraska Medical Center, Omaha, Nebraska, United States.
Infection Control and Hospital Epidemiology
|December 1, 2021
Summary
Global high-level isolation units (HLIUs) show varied infrastructure and capabilities, with most having treated high-consequence infectious diseases. Further research is needed to establish best practices for HLIU design and operations.
Area of Science:
- Infectious Diseases
- Public Health
- Healthcare Infrastructure
Background:
- High-level isolation units (HLIUs) are critical for managing high-consequence infectious diseases.
- Assessing the current state of global HLIUs is essential for preparedness.
- The National Emerging Special Pathogens Training and Education Center (NETEC) facilitates global collaboration.
Purpose of the Study:
- To evaluate the experience, infrastructure, and capabilities of high-level isolation units worldwide.
- To inform the development of best practices for HLIU design and operation.
- To identify areas for future research and guideline development.
Main Methods:
- An electronic survey was distributed to 22 global HLIUs.
- 19 HLIUs (86% response rate) provided data on organization, costs, staffing, and infection control.
- Descriptive statistics were used to analyze the collected data.
Main Results:
- The average annual budget for responding HLIUs was $484,615.
- 89% of HLIUs had experience treating patients with high-consequence infectious diseases.
- HLIUs reported a mean of 6.37 adult beds and 4.23 pediatric beds, with capacity varying by pathogen.
Conclusions:
- Responding HLIUs are among the most experienced globally, yet significant variations in infrastructure and capabilities exist.
- Unanswered technical questions regarding HLIU design, infection control, staffing, and training require further investigation.
- Continued global collaboration is necessary to define evidence-based best practices for HLIUs.
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