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Updated: Oct 11, 2025

Translational Rabbit Model of Chronic Cardiac Pacing
Published on: January 6, 2023
Inadvertent left ventricular pacing due to lead malpositioning, incidentally discovered seventeen years later
Shahid Bobat1,2, Wei Jun How2
1Department of Biology, Medicine and Health, The University of Manchester, Manchester, UK shahidbobat@doctors.org.uk.
Abstract:
Inadvertent lead malpositioning into the left ventricle (LV) is an uncommon complication of pacemaker lead implantation. It can have implications on clinical outcome due to ventricular dyssynchrony, and result in further complications such as thrombus formation with subsequent embolisation. This case study reports the clinical, electrocardiographic, plain film and echocardiographic findings of an 82-year-old male in whom the intravenous lead of a dual chamber pacemaker was unintentionally passed into the LV via an atrial septal defect. Inadvertent placement was discovered incidentally following the onset of atrial fibrillation (AF) 17 years later.
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