Self-Assembly of Upconversion Nanoparticles Based Materials and Their Emerging Applications
Zhen Zhang1, Yongming Chen1, Yong Zhang2,3
1School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, 510275, P. R. China.
Small (Weinheim an Der Bergstrasse, Germany)
|December 1, 2021
Summary
Recent advances in upconversion nanoparticles (UCNPs) assemblies enable multifunctional nanoplatforms for complex applications. This review details synthesis, applications like dual-modality imaging, and future challenges for UCNPs assemblies.
Area of Science:
- Nanotechnology
- Materials Science
- Biomedical Engineering
Background:
- Conventional upconversion nanoparticles (UCNPs) have advanced significantly, but complex applications demand multifunctional nanoplatforms.
- Nanoscience and nanotechnology developments drive the need for integrated UCNPs systems.
- Self-assembly offers a method to create composite UCNPs with tailored properties.
Purpose of the Study:
- To review recent advancements in the synthesis of UCNPs assemblies.
- To summarize diverse applications of UCNPs assemblies.
- To discuss challenges and potential solutions in the field of UCNPs assemblies.
Main Methods:
- Review of self-assembly strategies for UCNPs.
- Analysis of synthesis optimization for UCNPs assemblies.
- Compilation of application examples in imaging, delivery, detection, and therapy.
Main Results:
- UCNPs assemblies can be designed with properties derived from individual components and composite morphology.
- Optimized synthesis methods yield versatile UCNPs assemblies.
- Applications demonstrated include dual-modality cell imaging, molecular delivery, detection, and programmed therapy.
Conclusions:
- UCNPs assemblies represent an ideal nanoplatform for multimodal and multiplexed applications.
- Further research into synthesis optimization and addressing limitations is crucial for advancing UCNPs assembly technology.
- These assemblies hold significant potential for future biomedical and technological innovations.


