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Updated: Oct 11, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Multicomponent Synthesis and Investigations Fluorescence Activity of Chromenone-Pyrazole Compounds
Ghodsi Mohammadi Ziarani1, Shirin Mohammadsaeed2, Alireza Badiei3
1Department of Chemistry, Faculty of physics and chemistry, Alzahra University, P.O. Box 1993893973, Tehran, Iran. gmohammadi@alzahra.ac.ir.
Abstract:
A synthetic method is described to produce some chromenone-pyrazole derivatives through a one-pot multicomponent reaction using SrFe12O19 as a magnetic catalyst. This method provides quite a few merits, including the use of an effective and easy separable nanocatalyst, high yields of products, short reaction time, and easy work-up. Two of the products showed fluorescence properties, which have detected mercury ions without any interference with other ions. They can detect a tiny amount of mercury ions, which were comparable with other chemosensors. The detection limit is 4 × 10-7 and 3 × 10-8 M, respectively, for the compound I and II, respectively, which were considered very low amounts. The effect of mercury on health and environmental pollution is essential in medical science.
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