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Related Experiment Video

Updated: Oct 11, 2025

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation

Published on: September 23, 2017

Low Frequency Transcranial Alternating Current Stimulation Accelerates Sleep Onset Process.

Jiaxin Xie, Lin Wang, Chao Xiao

IEEE Transactions on Neural Systems and Rehabilitation Engineering : a Publication of the IEEE Engineering in Medicine and Biology Society

|December 1, 2021

Summary

This summary is machine-generated.

Low frequency transcranial alternating current stimulation (tACS) accelerated sleep onset during daytime naps. This brain stimulation technique may help individuals with sleep disorders fall asleep faster.

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Last Updated: Oct 11, 2025

Effects of Transcranial Alternating Current Stimulation on the Primary Motor Cortex by Online Combined Approach with Transcranial Magnetic Stimulation

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Published on: September 23, 2017

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Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation tACS

Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation tACS

Published on: January 22, 2016

Area of Science:

Neuroscience
Sleep Science
Neuromodulation

Background:

Sleep homeostasis is crucial for cognitive function and well-being.
Difficulty initiating sleep can be a symptom of various sleep disorders.
Non-invasive brain stimulation offers potential therapeutic avenues for sleep disturbances.

Purpose of the Study:

To investigate the efficacy of low-frequency (5 Hz) transcranial alternating current stimulation (tACS) in accelerating sleep onset during daytime naps.
To explore the effects of tACS on electroencephalography (EEG) patterns and sleep architecture.

Main Methods:

Thirty healthy subjects received 15 minutes of 5 Hz tACS applied to the dorsal lateral prefrontal cortex before a nap.
Electroencephalography (EEG) and behavioral indicators were recorded at baseline and during sleep.
Subjects maintained open eyes during stimulation delivery.

Main Results:

tACS significantly increased theta band power (1-7 Hz) and accelerated alpha activity attenuation.
Spindle activity occurred earlier, and the transition to Non-rapid eye movement (NREM) sleep was expedited.
Subjective alertness decreased upon waking after the nap, suggesting a more consolidated sleep.

Conclusions:

Low-frequency tACS can accelerate the sleep onset process.
This neuromodulation technique shows promise for alleviating sleep onset difficulties associated with sleep disorders.
Further research is warranted to explore the therapeutic potential of tACS for insomnia and other sleep-related conditions.