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Demographics and Risk Factors of Pediatric Pulmonary Hypertension Readmissions
Mukul Sehgal1, Amod Amritphale2, Shashank Vadayla3
1Pediatric Critical Care, University of South Alabama College of Medicine, Mobile, USA.
Insights
Pediatric pulmonary hypertension (PH) patients have higher 30-day readmission rates. Invasive ventilation, higher illness severity, and female gender increase readmission risk in these children.
Area of Science:
- Pediatric Cardiology
- Critical Care Medicine
- Health Services Research
Background:
- Pediatric pulmonary hypertension (PH) is a serious condition associated with significant morbidity and mortality.
- PH contributes to increased hospital readmission rates among pediatric patients.
- Identifying risk factors for readmission is crucial for improving patient outcomes.
Purpose of the Study:
- To evaluate risk factors and comorbidities associated with 30-day readmissions in pediatric PH patients.
- To compare readmission rates in pediatric PH patients to other pediatric diagnoses.
Main Methods:
- Utilized the National Readmission Database (NRD) for 2017.
- Included pediatric patients (<18 years) diagnosed with PH (ICD-10 codes).
- Performed statistical analysis using SPSS v25.0.
Main Results:
- The 30-day readmission rate for pediatric PH was 14.43%, significantly higher than other pediatric diagnoses (OR 4.02).
- Invasive mechanical ventilation (endotracheal tube or tracheostomy) and higher All Patients Refined Diagnosis Related Groups (APR-DRG) scores were linked to increased readmissions.
- Sepsis and respiratory infections were associated with lower readmission rates.
Conclusions:
- Pediatric PH is linked to elevated 30-day readmission rates.
- Factors such as invasive mechanical ventilation, Medicaid insurance, higher illness severity, and female gender predict higher readmission likelihood.
- The study identified key predictors for readmission, informing targeted interventions for high-risk pediatric PH patients.
Background And Objectives:
Pulmonary hypertension (PH) leads to significant morbidity and mortality in pediatric patients and increases the readmission rates for hospitalizations. This study evaluates the risk factors and comorbidities associated with an increase in 30-day readmissions among pediatric PH patients.
Methods:
National Readmission Database (NRD) 2017 was searched for patients less than 18 years of age who were diagnosed with PH based on the International Classification of Diseases, 10th Revision (ICD-10). Statistical Package for the Social Sciences (SPSS) software v25.0 (IBM Corp., Armonk, NY) was used for statistical analysis.
Results:
Of 5.52 million pediatric encounters, 10,501 patients met the selection criteria. The 30-day readmission rate of 14.43% (p < 0.001) was higher than hospitalizations from other causes {Odds Ratio (OR) 4.02 (3.84-4.20), p < 0.001}. The comorbidities of sepsis {OR 0.75 (0.64-0.89), p < 0.02} and respiratory infections {OR 0.75 (0.67-0.85), p < 0.001} were observed to be associated with lower 30-day readmissions. Patients who required invasive mechanical ventilation via endotracheal tube {OR 1.66 (1.4-1.96), p < 0.001} or tracheostomy tube {OR 1.35 (1.15-1.6), p < 0.001} had increased unplanned readmissions. Patients with higher severity of illness based on All Patients Refined Diagnosis Related Groups (APR-DRG) were more likely to get readmitted {OR 7.66 (3.13-18.76), p < 0.001}.
Conclusion:
PH was associated with increased readmission rates compared to the other pediatric diagnoses, but the readmission rate in this study was lower than one previous pediatric study. Invasive mechanical ventilation, Medicaid insurance, higher severity of illness, and female gender were associated with a higher likelihood of readmission within 30 days.
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