Preparticipation electrocardiogram screening in a Gulf Coast community: A prospective study
Lane A McLendon1, Madhuri S Mulekar2, Lynn A Batten3
1Department of Pediatric Cardiology, Cleveland Clinic Children's, Cleveland, Ohio.
Heart Rhythm O2
|December 8, 2025
Summary
Electrocardiogram (ECG) screening is more effective than questionnaires for detecting life-threatening cardiac conditions in young athletes. ECG identified critical pathologies missed by the American Heart Association (AHA) questionnaire, improving athlete safety.
Area of Science:
- Cardiology
- Sports Medicine
- Preventive Cardiology
Background:
- Sudden cardiac death (SCD) in young athletes is a critical concern in sports.
- Current screening methods, including questionnaires, have limitations in detecting underlying cardiac pathologies.
- Debate persists regarding the optimal screening strategy for young athletes.
Purpose of the Study:
- To compare the effectiveness of a 12-lead electrocardiogram (ECG) versus a preparticipation questionnaire in detecting life-threatening cardiac conditions in young athletes.
- To evaluate the sensitivity and specificity of both screening methods.
Main Methods:
- A prospective study involving 2604 students aged 5-22 years in coastal Alabama.
- Participants completed the 14-point American Heart Association (AHA) preparticipation questionnaire.
- All participants underwent a 12-lead ECG screening.
Main Results:
- The AHA questionnaire identified symptoms in 11.9% of students, but missed 66.0% of critical cardiac pathologies.
- The 12-lead ECG revealed abnormalities in 3.3% of students, with 100% sensitivity and 97.0% specificity for life-threatening conditions.
- ECG detected three cases of conditions associated with sudden cardiac arrest, only one of which was flagged by the questionnaire.
Conclusions:
- The 12-lead ECG is a superior screening tool for identifying life-threatening cardiac pathologies in young athletes compared to the AHA questionnaire.
- ECG screening demonstrates higher sensitivity and specificity, significantly reducing the risk of missed diagnoses.
- Implementing ECG screening can enhance the safety of young athletes by detecting conditions that questionnaires might overlook.
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