A comprehensive review of functional dyspepsia in pediatrics

Shamaila Waseem1, Logan Rubin2

  • 1Indiana University School of Medicine-Pediatric Gastroenterology, 705 Riley Hospital Drive ROC 4210, Indianapolis, IN, 46202, USA. shwaseem@iu.edu.

Insights

Functional dyspepsia, a common disorder, involves various factors and has specific diagnostic criteria. Treatments like hypnotherapy show promise in reducing pediatric symptoms and improving quality of life.

Area of Science:

  • Gastroenterology
  • Pediatric Health
  • Functional Gastrointestinal Disorders

Background:

  • Functional gastrointestinal disorders, including functional dyspepsia, are diagnosed by exclusion using Rome Foundation criteria.
  • Recent research clarifies mechanisms and treatments for functional dyspepsia, involving physiological, genetic, environmental, and psychological factors.
  • Functional dyspepsia presents with overlapping symptoms but has distinct criteria and subclasses: postprandial distress syndrome and epigastric pain syndrome.

Purpose of the Study:

  • To review the current understanding of functional dyspepsia mechanisms and diagnostic criteria.
  • To explore recent advancements in treatment options for functional dyspepsia in pediatric patients.
  • To highlight the impact of functional dyspepsia on pediatric quality of life.

Main Methods:

  • Review of clinical data and research on functional dyspepsia.
  • Application of Rome IV criteria for diagnosis.
  • Evaluation of various treatment modalities, including pharmacologic, behavioral, and alternative therapies like hypnotherapy.

Main Results:

  • Functional dyspepsia is multifactorial, involving factors like acid sensitivity, lipid sensitivity, and low-grade inflammation.
  • Rome IV criteria aid in diagnosing functional dyspepsia and differentiating it from other disorders.
  • Treatments such as hypnotherapy have demonstrated effectiveness in alleviating symptoms and improving quality of life in pediatric patients.

Conclusions:

  • Accurate diagnosis of functional dyspepsia relies on clinical evaluation and Rome IV criteria.
  • Multiple treatment strategies are available and effective for managing functional dyspepsia in children.
  • Functional dyspepsia significantly impacts pediatric quality of life, with potential long-term effects into adulthood.

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