Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[The vinyl-chloride disease].

G Veltman, C E Lange, G Stein

    Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
    |April 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Long-term exposure to vinyl chloride in PVC production caused significant health issues, including skin, vascular, bone, and nervous system damage, liver fibrosis, and cancer. Improved workplace conditions and new techniques have largely mitigated these occupational health risks.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Relationship between pest grasshopper densities and climate variables in the southern Pampas of Argentina.

    Bulletin of entomological research·2022
    Same author

    Detection of first gammaherpesvirus sequences in Central African bats.

    New microbes and new infections·2020
    Same author

    Analysis of adenovirus DNA detected in rodent species from the Democratic Republic of the Congo indicates potentially novel adenovirus types.

    New microbes and new infections·2020
    Same author

    Canine papillomavirus types 1 and 2 in classical papillomas: High abundance, different morphological associations and frequent co-infections.

    Veterinary journal (London, England : 1997)·2019
    Same author

    Equus caballus papillomavirus 8 (EcPV8) associated with multiple viral plaques, viral papillomas, and squamous cell carcinoma in a horse.

    Equine veterinary journal·2018
    Same author

    Pododermatitis in Captive and Free-Ranging Greater Flamingos (Phoenicopterus roseus).

    Veterinary pathology·2015
    Same journal

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    Same journal

    [Viral infections of the skin].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    Same journal

    [Viral exanthems in children].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    Same journal

    [Erratum to: Digital health applications and data protection].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    Same journal

    [Virus-induced exanthems in returning travellers].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    Same journal

    [Venous ulcus cruris-Surgical treatment].

    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
    See all related articles

    Area of Science:

    • Occupational Medicine
    • Toxicology
    • Environmental Health

    Context:

    • Workers in polyvinyl chloride (PVC) production face long-term exposure to vinyl chloride monomer (VCM).
    • VCM is a known human carcinogen linked to various systemic health effects.
    • Historical occupational exposure has led to documented health complications in PVC manufacturing workers.

    Purpose:

    • To outline the health risks associated with occupational exposure to vinyl chloride.
    • To detail the observed toxicological effects on multiple organ systems.
    • To highlight the effectiveness of workplace interventions in reducing VCM-related health hazards.

    Summary:

    • Long-term exposure to vinyl chloride in PVC production is associated with a spectrum of adverse health outcomes.

    Related Experiment Videos

  • Observed effects include dermatological, vascular, skeletal, hematological (thrombocytopenia), hepatic (fibrosis, portal hypertension), porphyrin metabolism disturbances, and central nervous system alterations.
  • Vinyl chloride is recognized as an oncogen, notably linked to angiosarcoma of the liver.

    • Impact:

    • Directed occupational medicine supervision and improved production conditions have significantly reduced workplace health risks.
    • Implementation of new processing techniques further contributes to mitigating the health hazards of VCM exposure.
    • This underscores the importance of stringent occupational safety measures in chemical manufacturing environments.