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Cyproterone Acetate-Induced Acute Liver Failure: A Case Report and Review of the Literature
Pramod Kumar1, Sujith Reddy1, Anand Kulkarni1
1Department of Hepatology and Liver Transplantation, Asian Institute of Gastroenterology Hospitals, Survey No 136, Mindspace Rd, Gachibowli, Hyderabad, Telangana 50003, India.
Abstract:
Cyproterone acetate (CPA), a hydroxyprogesterone derivative, is used to treat advanced prostate cancer and infrequently in women for acne, breast cancer and hirsutism. Transient mild elevation in levels of liver enzymes is reported in 10-30% of patients, and acute liver failure (ALF) is uncommon. Here, we discuss the first case of CPA-induced ALF from India and the available literature.
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