Neurosensory Prosthetics: An Integral Neuromodulation Part of Bioelectronic Device

Area of Science:

• Biomedical Engineering
• Neuroscience
• Immunology
• Molecular Biology

Background:

• Bioelectronic devices (BEDs) represent a convergence of multiple scientific disciplines.
• Bioelectronic medicines (BEMs) are a subset of BEDs utilizing neuromodulation principles.
• BEMs offer a novel therapeutic approach for managing chronic diseases.

Purpose of the Study:

• To review the expanding applications of BEDs in healthcare.
• To highlight the therapeutic potential of BEMs through neuromodulation.
• To discuss the diagnostic capabilities of BEDs, mimicking sensory systems.

Main Methods:

• Neuromodulation techniques including deep brain, vagal nerve, and spinal nerve stimulation.
• Development of sensory-mimicking BEDs like bioelectronic noses and tongues for diagnostics.
• Review of existing literature on BED applications across various health conditions.

Main Results:

• BEMs demonstrate efficacy in modifying neural circuits for therapeutic benefit.
• BEDs show promise as diagnostic tools by replicating in vivo neurosensory functions.
• The scope of BED applications is continually broadening across diverse medical fields.

Conclusions:

• BEMs and BEDs signify a new frontier in medical treatment and diagnostics.
• Neuromodulation is a key mechanism underlying BEM therapeutic actions.
• The integration of engineering with biological sciences is crucial for advancing BEMs and BEDs.