Related Experiment Video
Updated: Jul 29, 2025
08:09
CUBIC Protocol Visualizes Protein Expression at Single Cell Resolution in Whole Mount Skin Preparations
Published on: August 4, 2016
11.6K
Cubosome-based cosmeceuticals: A breakthrough in skincare
Srishti Shetty1, Saritha Shetty1
1Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKMs, NMIMS Deemed to Be University, Mumbai 400056, Maharashtra, India.
Drug Discovery Today
|May 24, 2023
Summary
Lyotropic liquid crystals (LLCs) offer a novel nanoparticle system for advanced skincare. Cubosomes, a type of LLC, show promise for effectively delivering cosmetic agents to target sites.
Area of Science:
- Cosmetic Science
- Materials Science
- Nanotechnology
Background:
- Nanotechnology enhances skincare formulations by enabling targeted delivery of active agents.
- Lyotropic liquid crystals (LLCs) are biocompatible and biodegradable nanoparticle systems.
- Cubosomes, a specific LLC structure, are explored for their potential in cosmetic applications.
Purpose of the Study:
- To review the structure and preparation methods of cubosomes.
- To investigate the potential of cubosomes as delivery vehicles for cosmetic agents.
- To highlight the application of cubosomes in advanced skincare formulations.
Main Methods:
- Literature review on cubosome structure and preparation.
- Analysis of cubosome characteristics for cosmetic agent delivery.
- Exploration of structure-function relationships in cubosomal systems.
Main Results:
- Cubosomes exhibit unique structural properties suitable for encapsulating and delivering cosmetic ingredients.
- Various methods exist for preparing cubosomes with tunable characteristics.
- The biocompatibility and biodegradability of LLCs, including cubosomes, are advantageous for topical applications.
Conclusions:
- Cubosomes represent a promising nanotechnology for enhancing the efficacy of skincare products.
- Further research into cubosome formulation can optimize cosmetic agent delivery.
- The application of cubosomes in cosmetics offers a pathway to more robust and targeted skincare solutions.
More Related Videos
10:05Genome-wide Mapping of Drug-DNA Interactions in Cells with COSMIC Crosslinking of Small Molecules to Isolate Chromatin
Published on: January 20, 2016
8.3K
11:07Visualizing and Quantifying Pharmaceutical Compounds within Skin using Coherent Raman Scattering Imaging
Published on: November 24, 2021
2.9K
Related Concept Videos
01:12Renewal of Skin Epidermal Stem Cells
2.6K
The skin is divided into epidermis, dermis, and hypodermis, the skin's outermost, middle, and inner layers. The human epidermal layer regularly undergoes renewal, where old, dead cells are replaced by new cells. Epidermal stem cells or EpiSCs divide and differentiate to restore the lost cells. For the renewal process, some EpiSCs continuously self-renew. In contrast, few others differentiate into transit-amplifying cells, which later form prickle or spinous cells, followed by granular...
2.6K
01:19Clinical Applications of Epidermal Stem Cells
2.7K
Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
2.7K
01:16Confocal Fluorescence Microscopy
13.4K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
13.4K
01:23Tissue Renewal without Stem Cells
1.8K
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
However, failure of such a system...
1.8K
01:17Studying the Cytoskeleton
6.3K
The cytoskeletal architecture can be studied using different microscopic and biochemical techniques. Electron microscopy was instrumental in discovering the cytoskeletal architecture around the 1960s, which allowed obtaining structural information at a high-resolution level. However, the sample preparation procedure often limits this ability in biological samples. Several protocols have been developed over the years to optimize sample preparation. In one of the protocols known as rotary...
6.3K
01:23Role of Skin in Vitamin D Synthesis
5.4K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
5.4K