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Updated: Oct 11, 2025

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Pediatric deep burn management after split-thickness autologous skin transplantation: A comparative study
Aba Lőrincz1, Anna Gabriella Lamberti1,2, Zsolt Juhász2
1Department of Thermophysiology, Institute for Translational Medicine, Medical School, University of Pécs, 12 Szigeti Street, Pécs, Hungary.
Insights
New dressings significantly reduced anesthesia and dressing changes for pediatric deep burn patients after skin grafting. This led to earlier healing and shorter hospital stays, improving patient outcomes.
Area of Science:
- Pediatric surgery
- Burn treatment
- Wound healing
Background:
- Deep pediatric burns present significant treatment challenges.
- Post-skin grafting care options for pediatric burns are numerous but lack comparative data.
- Optimizing wound management is crucial for reducing patient morbidity.
Purpose of the Study:
- To compare the effectiveness of two different postoperative dressing regimens for deep pediatric burns treated with split-thickness skin grafting.
- To evaluate the impact of Aquacel Ag foam and Curiosa gel versus traditional dressings on patient outcomes.
Main Methods:
- A cohort study analyzed 16 pediatric patients with deep second and third-degree burns treated between 2012 and 2020.
- Patients were divided into a comparison group (Grassolind/Mepitel and Betadine) and an intervention group (Aquacel Ag foam and Curiosa gel).
- Outcomes measured included number of anesthesia sessions, dressing changes, time to complete healing, and length of hospitalization.
Main Results:
- The intervention group (Aquacel Ag foam and Curiosa gel) required significantly fewer anesthesia sessions (43% reduction, P=.004) and dressing changes (84% reduction, P=.001).
- Complete wound healing occurred 3 days earlier in the intervention group.
- Mean hospitalization length was reduced by 45% in the intervention group compared to the control group.
Conclusions:
- Aquacel Ag foam and Curiosa gel represent a more effective postoperative dressing strategy for pediatric deep burns after skin grafting.
- This new approach significantly reduces the need for anesthesia and dressing changes, leading to faster healing and shorter hospital stays.
- Further research should explore long-term outcomes and cost-effectiveness of these advanced dressings in pediatric burn care.
Abstract:
Treatment of pediatric deep burns remains a challenge for healthcare personnel. After skin grafting, several treatment options are available, but comparative studies of the different options are scarce. Here, we compared the effectiveness of 2 postoperative dressings used to treat deep pediatric burns after split-thickness skin grafting.At the Department of Paediatrics, University of Pécs, 16 children received skin transplantation after the deep second and third-degree injuries between January 1, 2012 and December 31, 2020 whose results have been analyzed, in this cohort study. We compared the traditionally used Grassolind or Mepitel net and Betadine solution (comparison group) with Aquacel Ag foam and Curiosa gel (intervention group).Seven children were included in the comparison and 9 children in the intervention group. In the control group, the average number of anesthesia was 6.29, while the number of dressing changes was 4.29. After complete wound closure, the dressing's final removal was on the 13th day, while the mean length of hospitalization was 21.89 days. On average, in the intervention group, 3.56 anesthesia was induced, and 0.66 dressing changes were needed after transplantation. Complete healing (dressing removal) was on the 10th day, and the mean length of hospitalization was 12.38 days.In the intervention group, the need for anesthesia significantly decreased by 43% (P = .004), and they required 84% fewer dressing changes after transplantation (P = .001). Moreover, the dressing could be removed 3 days earlier, and the length of hospitalization was reduced by 45% on average.
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