Bloody nipple discharge in Carney complex: A case report
Julian K K Chan1, Natalia Garibotto2, Deepthi Dissanayake1
1Department of Radiology, Royal Perth Hospital, Perth, Western Australia, Australia.
The Breast Journal
|December 7, 2021
Summary
Carney complex (CNC) is a rare genetic disorder causing skin pigmentation and tumors. This case highlights CNC's breast manifestations, including bloody nipple discharge and multiple lumps, emphasizing the need for awareness in imaging.
Area of Science:
- Endocrinology
- Genetics
- Oncology
Background:
- Carney complex (CNC) is an autosomal dominant disorder.
- Characterized by skin pigmentation, mucosal lesions, and multiple endocrine/nonendocrine tumors.
- Breast tumors in CNC are typically benign, multiple, and include myxoid fibroadenomas and intraductal papillomas.
Observation:
- A young female patient with a known diagnosis of Carney complex presented with significant clinical symptoms.
- The patient exhibited copious bloody nipple discharge.
- Multiple breast lumps were detected during examination.
Findings:
- The case underscores the diverse breast manifestations in Carney complex.
- Imaging features of CNC-related breast conditions require careful evaluation.
- Bloody nipple discharge and multiple breast lumps can be indicative of CNC in affected individuals.
Implications:
- Increased recognition of CNC's breast involvement is crucial for accurate diagnosis.
- Multidisciplinary approaches are essential for managing patients with Carney complex.
- Further research into the specific breast imaging characteristics of CNC is warranted.
