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Updated: Oct 10, 2025

06:37
Immunolabelling Myofiber Degeneration in Muscle Biopsies
Published on: December 5, 2019
9.1K
[Targeting macrophages in muscular dystrophies?]
1Institut NeuroMyoGène, Université Claude Bernard Lyon 1, CNRS UMR 5310, Inserm U1217, Université de Lyon, 69007 Lyon, France.
Abstract:
Macrophages play an essential role during muscle regeneration. Alteration of their properties is observed in chronic diseases such as degenerative myopathies, where they contribute to muscle fibrosis. Modulation of macrophage inflammatory status represents a relevant therapeutic strategy to improve muscle homeostasis.

