Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optimal pulsing sequences for MR contrast agents.

G L Wolf, P M Joseph, E J Goldstein

    AJR. American Journal of Roentgenology
    |August 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Pulmonary rehabilitation for post-TB lung disease led by TB survivors.

    Public health action·2025
    Same author

    Impact of implementing respiratory point-of-care testing in a regional haemato-oncology unit.

    The Journal of hospital infection·2020
    Same author

    In-house validation of the cobas Liat influenza A/B and RSV assay for use with gargles, sputa and endotracheal secretions.

    The Journal of hospital infection·2018
    Same author

    Response to Bhaskaran et al's "Effects of air pollution on the incidence of myocardial infarction".

    Heart (British Cardiac Society)·2010
    Same author

    A novel hypothesis to explain associations of carbon monoxide and nitrogen dioxide with deaths from respiratory disease.

    Journal of epidemiology and community health·2009
    Same author

    Coated-platelets in ischemic stroke: differences between lacunar and cortical stroke.

    Journal of thrombosis and haemostasis : JTH·2008
    Same journal

    The Banality of Cancer: Entropy As a Third Pillar of Lung Nodule Risk Assessment.

    AJR. American journal of roentgenology·2026
    Same journal

    A Narrow Window for Artificial Intelligence-Generated Synthetic Temporal Bone CT From MRI.

    AJR. American journal of roentgenology·2026
    Same journal

    From Uncertainty to Actionable Management: The Isolated Abnormal Axillary Lymph Node.

    AJR. American journal of roentgenology·2026
    Same journal

    Beyond Detection: Translating Artificial Intelligence-Driven Opportunistic Screening Into Clinical Action.

    AJR. American journal of roentgenology·2026
    Same journal

    Navigating PSMA PET Radiopharmaceuticals: Clinical and Operational Factors.

    AJR. American journal of roentgenology·2026
    Same journal

    From Mesenteric Ischemia to Intestinal Stroke.

    AJR. American journal of roentgenology·2026
    See all related articles

    Paramagnetic metal chelates used as MRI contrast agents enhance liver and bile imaging. Optimal imaging of these agents is achieved with short repetition time (TR) and echo-delay time (TE) sequences.

    Area of Science:

    • Medical Imaging
    • Radiology
    • Biochemistry

    Background:

    • Paramagnetic metal chelates are utilized as contrast agents in Magnetic Resonance Imaging (MRI).
    • Certain contrast agents are eliminated via biliary excretion, impacting liver and bile characteristics.
    • These agents significantly alter proton relaxation times (T1 and T2) in the liver and bile.

    Purpose of the Study:

    • To investigate the influence of paramagnetic contrast agents on MRI parameters.
    • To determine optimal imaging parameters for visualizing the effects of these contrast agents.
    • To evaluate the impact of repetition time (TR) and echo-delay time (TE) on image quality.

    Main Methods:

    • Studies were conducted on rabbits, both with and without the administration of contrast agents.

    Related Experiment Videos

  • Various repetition times (TR) and echo-delay times (TE) were employed.
  • Image quality was assessed based on the visualization of liver and bile.

    • Main Results:

    • Contrast agents significantly reduced proton T1 and T2 relaxation times in the liver and bile.
    • Short TR and short TE imaging sequences proved most effective for visualizing the contrast agent effects.
    • Excellent liver images were obtained using TR = 80 msec, TE = 10 msec, with two excitations, and a 20-second imaging time.

    Conclusions:

    • Paramagnetic contrast agents offer valuable diagnostic information in liver and bile MRI.
    • Short TR and TE pulse sequences are recommended for optimal imaging of these contrast agents.
    • Understanding the impact of contrast agents on relaxation times is crucial for selecting appropriate MRI sequences.