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Related Concept Videos

Computed Tomography01:10

Computed Tomography

6.9K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Related Experiment Video

Updated: Oct 10, 2025

Automated Midline Shift and Intracranial Pressure Estimation based on Brain CT Images
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The Reliability of Measuring Early Brain Edema with Computed Tomography.

Yi-Fang Fan1, Mi Shen2, Xin-Xin Wang1

  • 1Department of Anesthesiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.

Current Medical Imaging
|December 9, 2021
PubMed
Summary

Computed Tomography (CT) reliably measures early postoperative brain edema in high-grade glioma patients after craniotomy, showing substantial agreement with Magnetic Resonance Imaging (MRI). This finding supports CT

Keywords:
ICCPostoperativebrain edemacomputed tomographyhigh-grade gliomamagnetic resonance imaging

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Area of Science:

  • Neurosurgery
  • Radiology
  • Oncology

Background:

  • Postoperative brain edema is a frequent complication following craniotomy for high-grade glioma.
  • While Magnetic Resonance Imaging (MRI) is typically preferred for diagnosing brain edema, its use in the acute postoperative phase is limited.
  • The reliability of Computed Tomography (CT) for early detection of postoperative brain edema remains uncertain.

Purpose of the Study:

  • To investigate the agreement and correlation between CT and MRI in quantifying early postoperative brain edema.
  • To assess the reliability of CT in detecting brain edema in the immediate postoperative period.

Main Methods:

  • Retrospective analysis of 20 high-grade glioma patients who underwent craniotomy.
  • Manual outlining of regions of interest and operative cavities to measure brain edema volume on both CT and MRI.
  • Statistical evaluation using Pearson correlation and Intraclass Correlation Coefficient (ICC) to determine agreement and association.

Main Results:

  • Excellent interrater agreement for brain edema detection was observed for both CT (ICC=0.977) and MRI (ICC=0.963).
  • A significant positive correlation (r=0.97) and excellent consistency (ICC=0.934-0.957) were found between CT and MRI measurements of brain edema volume.
  • Both modalities demonstrated substantial comparability in detecting postoperative brain edema.

Conclusions:

  • CT imaging demonstrates substantial comparability with MRI for detecting postoperative brain edema.
  • CT is a reliable tool for measuring brain edema volume in the early postoperative stage after glioma surgery.