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Updated: Jun 7, 2026

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
10:37

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Published on: November 15, 2017

Author Correction: A computational method for detection of ligand-binding proteins from dose range thermal proteome

Nils Kurzawa1,2, Isabelle Becher1, Sindhuja Sridharan1,3

  • 1European Molecular Biology Laboratory, Genome Biology Unit, Meyerhofstrasse 1, Heidelberg, 69117, Germany.

Nature Communications
|December 9, 2021
PubMed
Summary

No abstract available in PubMed .

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Ligand Binding Sites

Proteins are dynamic macromolecules that carry out a wide variety of essential processes; however, the activities of most proteins depend on their interactions with other molecules or ions, known as ligands.
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...

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