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A Multi-Center Disclusion Time Reduction (DTR) Randomized Controlled Occlusal Adjustment Study Using Occlusal Force
Prafulla Thumati1, Roshan P Thumati2, Shwetha Poovani1
1Department of Prosthodontics, Raja Rajeswari Dental College and Hospital, Bengaluru 560074, India.
Sensors (Basel, Switzerland)
|December 10, 2021
Summary
Investigational ICAGD coronoplasty significantly reduced pain, functional restrictions, and depression in dental students within one week, with sustained benefits over six months. Tooth polishing showed no placebo effect.
Area of Science:
- Dental Science
- Biomedical Engineering
- Clinical Research
Background:
- Temporomandibular disorders (TMD) and associated symptoms like pain and depression are prevalent.
- Disclusion time, the period during which posterior teeth are out of contact during mandibular movement, is implicated in TMD.
- Objective measurement of disclusion time and its impact on patient-reported outcomes requires further investigation.
Purpose of the Study:
- To evaluate the efficacy of ICAGD coronoplasty in reducing disclusion time and improving patient-reported outcomes.
- To assess the impact of ICAGD coronoplasty on pain, functional restrictions, and depressive symptoms.
- To determine if tooth polishing acts as a placebo in this context.
Main Methods:
- A Randomized Controlled Trial (RCT) involving 100 dental students was conducted across five dental colleges.
- Participants were assigned to either ICAGD coronoplasty (treatment) or tooth polishing (control).
- Intraoral sensors, muscular electrodes, and validated questionnaires (Beck Depression Inventory-II, Functional Restrictions, Chronic Pain Symptom and Frequency) were used to collect data at baseline and at 1 week, 1 month, 3 months, and 6 months post-intervention.
Main Results:
- Pre-treatment, Disclusion Times, BDI-II scores, and Symptom Scales were comparable between groups.
- The ICAGD group showed significant reductions in Disclusion Times, BDI-II scores, and Symptom Scales from 1 week up to 6 months (p < 0.05).
- The control group did not exhibit similar improvements, and the tooth polishing intervention did not yield a placebo response.
Conclusions:
- ICAGD coronoplasty is an effective treatment for reducing pain, functional restrictions, symptom frequency, and emotional depression.
- The positive effects of ICAGD coronoplasty are evident within one week and are sustained for at least six months.
- Tooth polishing does not appear to induce a placebo effect for these symptoms.

