Fibroblasts Adhesion to Laser-Modified Titanium Surfaces-A Systematic Review.

Area of Science:

• Biomaterials Science
• Dental Implantology
• Cell Biology

Background:

• Laser treatments are increasingly used in implant dentistry.
• Titanium surfaces are common in dental implants.
• Fibroblast adhesion is critical for osseointegration.

Purpose of the Study:

• To systematically review how laser modification of titanium surfaces affects fibroblast adhesion.
• To answer the question: "How does laser modification of titanium surface influence fibroblast adhesion?"

Main Methods:

• A systematic literature search was conducted on PubMed and Scopus databases.
• Keywords included: laser, fibroblast, titanium, implant/disc, proliferation/adhesion.
• Ten studies with a low risk of bias were included in the review.

Main Results:

• Laser-modified titanium surfaces showed enhanced fibroblast adhesion and metabolic activity.
• Optimal fibroblast adhesion was observed with three-directional laser application.
• Energy density above 0.75 J/cm² significantly improved cell adhesion.
• Increased titanium surface wettability positively influenced cell adhesion.

Conclusions:

• Laser modification of titanium surfaces positively impacts fibroblast adhesion.
• The appropriate laser energy dose is critical for successful outcomes.
• Further research into optimal laser parameters is warranted for clinical application.