Plasma therapy: a passive resistance against the deadliest

Area of Science:

• Immunology
• Infectious Diseases
• Hematology

Background:

• Convalescent plasma therapy is an established treatment for infectious diseases.
• Its efficacy is notable in situations lacking specific therapeutic strategies.
• The COVID-19 pandemic has renewed interest in this therapeutic approach.

Purpose of the Study:

• To review the application of convalescent plasma therapy across various diseases.
• To elucidate the potential mechanisms of action for this therapy.
• To trace the historical development of blood-derivative therapeutics.

Main Methods:

• Literature review of convalescent plasma therapy applications.
• Analysis of historical advancements in blood-derivative treatments.
• Discussion of immunoglobulins and their therapeutic roles.

Main Results:

• Convalescent plasma therapy has demonstrated utility in managing infectious diseases.
• The therapy's application extends to both infectious and non-infectious conditions.
• Evolution of treatments ranges from animal sera to targeted human immunoglobulins.

Conclusions:

• Convalescent plasma remains a significant therapeutic option for infectious diseases.
• Understanding its mechanisms is crucial for optimizing treatment.
• The progression of blood-derivative therapies highlights advancements in medical treatment.