Related Experiment Video
Updated: Oct 10, 2025

Directed Protein Packaging within Outer Membrane Vesicles from Escherichia coli: Design, Production and Purification
Published on: November 16, 2016
Side-chain Packing Using SE(3)-Transformer
Akhil Jindal1, Sergei Kotelnikov, Dzmitry Padhorny
1Department of Applied Mathematics and Statistics, Stony Brook University, Stony Brook, NY 11794, United States.
Abstract:
Predicting protein side-chains is important for both protein structure prediction and protein design. Modeling approaches to predict side-chains such as SCWRL4 have become one of the most widely used tools of its type due to fast and highly accurate predictions. Motivated by the recent success of AlphaFold2 in CASP14, our group adapted a 3D equivariant neural network architecture to predict protein side-chain conformations, specifically within a protein-protein interface, a problem that has not been fully addressed by AlphaFold2.
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