Paper-based field-effect transistor sensors

Area of Science:

• Materials Science and Engineering
• Biomedical Engineering
• Analytical Chemistry

Background:

• Growing demand for affordable, fast, recyclable, and flexible electronic devices for biosensing applications.
• Development and validation of various paper-based devices, including microfluidic paper electrodes, diodes, and transistors.
• Existing fabrication techniques for paper-based field-effect transistor (PFET) sensors prioritize economic and eco-friendly methods.

Purpose of the Study:

• To review fabrication techniques and performance of various PFET sensors.
• To discuss challenges and future prospects in PFET biosensing technology for biomedical applications.
• To highlight the sustainable nature of PFETs for wearable electronics.

Main Methods:

• Comprehensive literature review of PFET sensor fabrication methods.
• Analysis of performance metrics for different types of PFET sensors.
• Discussion of modifications (organic/inorganic) and their impact on analyte detection.

Main Results:

• PFETs are synthetic-free, mechanically flexible, biocompatible, and offer signal amplification, making them suitable for wearables.
• Modified PFETs act as transducers, identifying analytes via electrical signals.
• Challenges remain in achieving high signal-to-noise ratios, specificity, and rapid detection with modified PFETs.

Conclusions:

• PFET biosensing technology presents significant potential for various analytical and biomedical applications.
• Overcoming challenges in specificity and detection speed is crucial for advancing PFET applications.
• The sustainable nature of PFETs positions them as a promising technology for future electronic devices.