Optimal Scanning Protocol for Optical Tomography

Tomography is a two step process in which the sample under test is first scanned by the hardware of the system to acquire data and then the operating software reconstruct images from the gathered information. The main objective of this work is to optimize the scanning process to acquire maximum amount of information in each measurement when the system is scanning the sample. By exploiting our prior information about the sample and using estimation theory, we developed a systematic approach to implement the optimal scanning protocol. Results of this study provide strong evidence that the developed algorithms can speed up data acquisition. Also it is shown that the proposed method can reduce the impact of noise as well as improving the reconstruction error while performing less number of measurements.Clinical relevance- The proposed method can enhance data acquisition time, exposure dosage and cost of operation in medical applications of tomography.