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An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
Directive clinique no 422e : Ménopause et maladies cardiovasculaires
Beth L Abramson1, Denise R Black2, Marie K Christakis3
1Toronto, Ont..
This guideline provides evidence-based strategies to enhance care for women experiencing perimenopause or menopause. It offers updated scientific information to healthcare providers for informed patient decision-making regarding symptom management.
Area of Science:
- Reproductive Medicine
- Women's Health
- Evidence-Based Practice
Background:
- Addresses the need for updated clinical guidance on managing perimenopausal and menopausal symptoms.
- Highlights the importance of evidence-based information for healthcare providers and patients.
Framework:
- Systematic literature review of publications from 2002-2020.
- Utilizes the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework for evidence quality and recommendation strength.
Implementation:
- Information disseminated to healthcare professionals including physicians, nurses, and pharmacists.
- Empowers women with choices for therapeutic options, including the status quo, for menopause-related symptoms and morbidities.
Implications:
- Aims to improve the quality of care for women in perimenopause and menopause.
- Facilitates informed patient-provider discussions on managing menopausal transitions and associated health concerns.
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