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Gross Anatomy of the Liver01:17

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Updated: Oct 10, 2025

Measurement of the Hepatic Venous Pressure Gradient and Transjugular Liver Biopsy
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Transjugular Liver Biopsy.

Claire S Kaufman1, Maxwell R Cretcher2

  • 1Department of Radiology, University of Utah, Salt Lake City, UT.

Techniques in Vascular and Interventional Radiology
|December 13, 2021
PubMed
Summary
This summary is machine-generated.

Transjugular liver biopsy (TJLB) is a vital interventional radiology procedure for patients unsuitable for percutaneous biopsy. Despite smaller samples, TJLB provides adequate tissue for liver diagnosis and staging.

Keywords:
Transjugular liver biopsybiopsyelevated liver function testsliver transplantportal hypertension

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Area of Science:

  • Interventional Radiology
  • Hepatology
  • Vascular Procedures

Background:

  • Transjugular liver biopsy (TJLB) has been a standard interventional radiology procedure since 1970.
  • It is indicated when percutaneous liver biopsy is contraindicated, such as in cases of ascites or coagulopathy.
  • TJLB is also used for patients evaluated for portal hypertension.

Purpose of the Study:

  • To provide interventional radiologists with essential knowledge regarding TJLB.
  • To cover indications, work-up, technical aspects, and potential complications of TJLB.

Main Methods:

  • Review of indications for TJLB, including patient conditions like ascites and coagulopathy.
  • Discussion of technical details, tips, and tricks for performing TJLB.
  • Analysis of potential complications associated with the procedure.

Main Results:

  • TJLB specimens may be smaller with less complete portal triads compared to percutaneous samples.
  • Numerous studies confirm that TJLB samples are adequate for diagnosis and staging of liver conditions.
  • The procedure is a safe and effective alternative when other biopsy methods are not feasible.

Conclusions:

  • TJLB is a crucial diagnostic tool in interventional radiology for specific patient populations.
  • Adequacy of TJLB samples for diagnosis and staging is well-established.
  • Understanding the nuances of TJLB is essential for successful patient management.