Non-tropical idiopathic splenomegaly and chronic T cell lymphocytosis

Non-tropical idiopathic splenomegaly (NTIS) is thought to predispose to the development of lymphoid neoplasia of B-cell type. We report a case of NTIS that evolved into a T-lymphoproliferative disorder. Review of the literature suggests that this type of evolution is not uncommon. The role of splenectomy in this progression is discussed.