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A Protocol for a Systematic Review and Meta-Analysis of Hospital Readmissions Following Acute Upper Gastrointestinal
Sandeep Kaur1, Cody L Dunne2, Lauren Bresee3
1Gastroenterology, Cumming School of Medicine, University of Calgary, Calgary, CAN.
Insights
This systematic review will analyze upper gastrointestinal bleed (UGIB) readmission rates and related outcomes. Findings will inform patient safety and healthcare resource use following UGIB hospitalization.
Area of Science:
- Gastroenterology and Hepatology
- Health Services Research
- Clinical Epidemiology
Background:
- Upper gastrointestinal bleeding (UGIB) is a significant cause of hospitalization.
- Readmission after UGIB poses risks to patient safety and impacts healthcare resource utilization.
- Understanding readmission patterns is crucial for quality improvement initiatives.
Purpose of the Study:
- To systematically review and meta-analyze all-cause readmission rates following hospitalization for upper gastrointestinal bleeding (UGIB).
- To investigate secondary outcomes including GI bleed-specific readmissions, mortality, readmission diagnoses, and length of stay.
- To explore readmission risk in high-risk subgroups based on age, sex, bleed type, anticoagulation, and comorbidities.
Main Methods:
- Systematic review and meta-analysis protocol.
- Comprehensive literature search for relevant studies.
- Data extraction and synthesis for primary and secondary outcomes.
Main Results:
- Anticipated to quantify all-cause and GI bleed-specific readmission rates.
- Will identify key factors associated with readmission and mortality.
- Will provide insights into readmission diagnoses and length of stay.
Conclusions:
- The findings will serve as a critical quality indicator for UGIB care.
- This review will inform strategies to enhance post-discharge patient safety.
- Results will guide efforts to optimize healthcare resource utilization for UGIB patients.
Abstract:
This protocol outlines the planned methodology for a systematic review and meta-analysis. The primary objective of the review is to identify all-cause readmission rates for individuals hospitalized for an upper GI bleed (UGIB). Secondary objectives will include GI bleed-specific readmission rates, mortality (all-cause and GI bleed-specific), readmission diagnosis, and length of stay on readmission visit. High-risk subgroups will also be explored including age, sex, type of GI bleed (e.g., variceal or not), anti-coagulation status, and comorbidity status. Through this review, the research team aims to describe an important quality indicator, which has implications for both patient safety post-discharge after an UGIB and healthcare resource utilization.
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