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Updated: Oct 10, 2025

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A Data-Driven Approach to Quantifying Immune States in Sepsis
Published on: February 7, 2025
337
The new discrete distribution with application to COVID-19 Data.
Ehab M Almetwally1,2, Doaa A Abdo3, E H Hafez4
1Faculty of Business Administration, Delta University of Science and Technology, Gamasa, 11152, Egypt.
Summary
Researchers developed a new discrete probability model, the discrete Marshall-Olkin Inverse Toppe-Leone (DMOITL) distribution, for analyzing count data. This model was applied to COVID-19 data and compared estimation methods using simulations.
Area of Science:
- Statistics
- Epidemiology
- Probability Theory
Background:
- Discrete distributions are crucial for analyzing count data, such as disease incidence.
- The Marshall-Olkin family and inverse Toppe-Leone distribution are important in statistical modeling.
- Modeling infectious diseases like COVID-19 requires robust statistical tools.
Purpose of the Study:
- To introduce a novel two-parameter discrete distribution, the discrete Marshall-Olkin Inverse Toppe-Leone (DMOITL) distribution.
- To model COVID-19 data from various countries (Italy, Puerto Rico, Singapore).
- To evaluate the performance of classical (maximum likelihood) and Bayesian estimation methods for the new distribution.
Main Methods:
- A new discrete distribution was derived using the survival discretization method.
- Properties such as reliability measures and moment functions were derived.
- Parameter estimation was performed using maximum likelihood and Bayesian methods.
- Monte Carlo simulations were used to compare estimation techniques.
- Highest posterior density (HPD) credible intervals were utilized with Markov Chain Monte Carlo (MCMC).
Main Results:
- The DMOITL distribution was successfully formulated and its properties derived.
- Both maximum likelihood and Bayesian methods provided valid parameter estimations.
- Simulation results offered insights into the comparative performance of the estimation techniques.
- HPD intervals demonstrated the utility of MCMC in assessing parameter uncertainty.
Conclusions:
- The DMOITL distribution offers a flexible new tool for count data analysis, including epidemiological modeling.
- The study validates the application of both maximum likelihood and Bayesian estimation for the DMOITL distribution.
- The findings contribute to the statistical methodology for disease modeling and parameter estimation.
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