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Innocuous presentation of ameloblastic carcinoma
Swagatika Panda1, Rupsa Das2, Diksha Mohapatra1
1Oral and Maxillofacial Pathology and Microbiology, Institute of Dental Sciences, Siksha O Anusandhan deemed to be University, Bhubaneswar, Odisha, India.
BMJ Case Reports
|December 15, 2021
Summary
Ameloblastic carcinoma, a rare odontogenic neoplasm, can present subtly. This case highlights the importance of histopathology for diagnosing this malignancy, even with innocuous clinical signs.
Area of Science:
- Oral Pathology
- Oncology
- Odontogenic Neoplasms
Background:
- Ameloblastic carcinoma is a rare malignant odontogenic neoplasm with varied presentations.
- Limited reports hinder understanding of its typical demographics and clinical/radiological features.
- The efficacy of adjuvant therapies like radiotherapy and chemotherapy remains unsubstantiated.
Observation:
- A 55-year-old male presented with an ameloblastic carcinoma.
- The case exhibited innocuous clinical and radiological features, masking its malignant nature.
- Diagnostic confirmation was solely achieved through histopathological evaluation.
Findings:
- Histopathological evaluation is crucial for diagnosing ameloblastic carcinoma, especially when clinical signs are non-specific.
- This case underscores the diagnostic challenges posed by ameloblastic carcinoma's diverse presentations.
- Reviewing differential diagnoses and treatment options in light of existing literature is essential.
Implications:
- Increased dentist awareness of ameloblastic carcinoma is needed.
- Further case reports and systematic reviews can improve understanding and management strategies.
- This case contributes to the limited body of knowledge on ameloblastic carcinoma, aiding future diagnostic and therapeutic decisions.
