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Intralesional Agents in Dermatology: Pros and Cons
Jagdish Sakhiya1, Dhruv Sakhiya2, Jitesh Kaklotar1
1Sakhiya Skin Clinic, 2nd Floor, Ayush Doctor House, Station-Lal Darwaja Road, Surat, Gujarat, India.
Journal of Cutaneous and Aesthetic Surgery
|December 15, 2021
Summary
Intralesional (IL) agents are a safe and effective dermatological treatment for various skin conditions. However, practitioners must weigh the benefits against potential side effects like pain, infection, and skin changes.
Area of Science:
- Dermatology
- Dermatopathology
Background:
- Intralesional (IL) therapy involves direct injection into skin lesions.
- Established in 1961, it's a common dermatological procedure.
Purpose of the Study:
- To review the advantages and disadvantages of intralesional agents in contemporary dermatology.
- To provide a balanced perspective on IL therapy.
Main Methods:
- Literature review of intralesional agent applications and outcomes.
- Analysis of reported efficacy and adverse events.
Main Results:
- IL therapy is safe, simple, and versatile for numerous skin conditions.
- Potential adverse effects include immediate (pain, bleeding, infection, allergy) and delayed (atrophy, telangiectasia, pigmentary changes, striae) complications.
Conclusions:
- Intralesional agents offer significant benefits but require careful consideration of risks.
- Understanding the pros and cons is crucial for optimal patient management in dermatology.
Keywords:
5-FluorouracilBecause intralesional agents are relatively safe, easy to implement, and effective in a broad spectrum of dermatological indication with excellent success rate and minimum systemic side effects, the trends in its use have been emerging nowadays. Pros over the cons make it a preferred choice in the dermatology field.bleomycinbotulinum toxin-A and hyaluronic acid fillerscorticosteroidscryotherapyimmunotherapyintralesional agentsmesotherapyplatelet-rich plasma
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