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Updated: Oct 10, 2025

Vascularized Composite Upper Limb Allograft Harvesting for Proximal Arm Allotransplantation
Published on: June 13, 2025
Invasive cutaneous squamous cell carcinoma resulting in arm amputation. Case discussion and literature review
Inez Eiben1, Darab Bahadori2, Paola Eiben3
1Department of Plastic Surgery, Guy's and St Thomas' Hospital NHS Foundation Trust, London, UK.
Abstract:
Skin cancer is one of the most common cancers in the world. Specifically incidence of non-melanoma malignancy in the UK has increased by 56% in the last decade. Cutaneous squamous cell carcinoma (cSCC) is a type of non-melanoma skin cancer that if caught early can be successfully treated. Conservative excision surgery is the most common treatment modality with high cure rates even if tumours are advanced. Radical surgery is rarely required, and amputations, especially when the distal part of the upper extremity is involved, are very uncommon. Here, we describe a case of an invasive cutaneous squamous cell carcinoma of the elbow that required trans-humeral arm amputation.
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