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Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiae
Jessica Emanuella Rocha Paz1, Priscila Oliveira Costa2, Albert Alexandre Costa Souza2
1Department of Oral & Maxillofacial Surgery and Periodontology, São Paulo University, School of Dentistry, Ribeirão Preto, SP, Brazil.
Objectives:
This study aimed to evaluate the effects on bone repair of different concentrations of mineral trioxide aggregate (MTA) added to AH Plus.
Materials And Methods:
Bone tissue reactions were evaluated in 30 rats (Rattus norvegicus) after 7 and 30 days. In the AH + MTA10, AH + MTA20, and AH + MTA30 groups, defects in the tibiae were filled with AH Plus with MTA in proportions of 10%, 20% and 30%, respectively; in the MTA-FILL group, MTA Fillapex was used; and in the control group, no sealer was used. The samples were histologically analyzed to assess bone union and maturation. The Kruskal-Wallis and Mann-Whitney tests were performed for multiple pairwise comparisons (p ≤ 0.05).
Results:
At the 7-day time point, AH + MTA10 was superior to MTA-FILL with respect to bone union, and AH + MTA20 was superior to MTA-FILL with respect to bone maturity (p < 0.05). At the 30-day time point, both the AH + MTA10 and AH + MTA20 experimental sealers were superior not only to MTA-FILL, but also to AH + MTA30 with respect to both parameters (p < 0.05). The results of the AH + MTA10 and AH + MTA20 groups were superior to those of the control group for both parameters and experimental time points (p < 0.05).
Conclusions:
The results suggest the potential benefit of using a combination of these materials in situations requiring bone repair.
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