Related Experiment Video
Updated: Oct 10, 2025

External Cephalic Version: Is it an Effective and Safe Procedure?
Published on: June 6, 2020
The center-effect on outcomes for infants born at less than 25 weeks
Nitya Nair1, Ravi Mangal Patel1
1From the Division of Neonatal-Perinatal Medicine, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, 2015 Uppergate Dr. NE, Atlanta, GA.
Abstract:
Marked variation exists in the care of infants born at <25 weeks' gestation. The center or location where a fetus or infant is cared for influences outcomes at very early gestational ages. Understanding this "center-effect," including characteristics associated with centers that have high survival of births at <25 weeks' gestation, may inform future studies and guide care practices to improve outcomes. This review focuses on the impact that the location or center of birth has on survival and other important outcomes for infants born at <25 weeks' gestation. We review potential sources of variation in care practices and other factors that might explain the "center-effect."
Related Concept Videos
Regression Toward the Mean
Factors Affecting Drug Response: Overview
Teratogenicity
Fetal Circulation
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...

