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An unusual cause of ascites: Castleman disease
XiuLi Zhu1, Si Chen2, Fang Fang2
1Department of Gastroenterology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230001, Anhui, People's Republic of China. 1216243099@qq.com.
Insights
Castleman disease (CD) is a rare lymphoproliferative disorder often misdiagnosed. This case highlights CD as a consideration for patients with unexplained ascites.
Area of Science:
- Hematology
- Oncology
- Rare Diseases
Background:
- Castleman disease (CD) is a rare lymphoproliferative disorder.
- CD shares histological features with infections, autoimmune diseases, and malignancies, leading to diagnostic challenges.
- Clinical heterogeneity and limited understanding of CD pathology contribute to diagnostic difficulties.
Background:
Castleman disease (CD) is a group of rare lymphoproliferative diseases with common lymph node histological features that can easily be misdiagnosed as infections, multiple autoimmune diseases, and malignant tumors.
Case Presentation:
Here we report a rare case of a Chinese male with refractory ascites for two years and was eventually diagnosed as CD.
Conclusions:
The challenges in diagnosis of CD arise from the large differential, clinical heterogeneity and our limited understanding of pathology. In case of rare ascites, CD needs to be considered.
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