Related Experiment Video
Updated: Oct 9, 2025

Improved Home Blood Pressure Control by CT-guided Ozone-mediated Renal Denervation for Patients with Resistant Hypertension
Published on: June 6, 2025
Blood Pressure Control and Adherence to Drug Treatment in Patients with Hypertension Treated at a Specialized
Mayra Cristina da Luz Pádua Guimarães1, Juliana Chaves Coelho1, Giovanio Vieira da Silva2
1Graduate Program in Adult Health Nursing (PROESA), University of São Paulo Nursing School, São Paulo, SP, Brazil.
Insights
High adherence to hypertension medication was observed in 90.1% of patients. However, blood pressure control was less frequent, influenced by marital status and prescribed medications.
Area of Science:
- Cardiology
- Clinical Pharmacy
- Public Health
Background:
- Hypertension management requires consistent adherence to antihypertensive drug treatment.
- Effective blood pressure control is crucial for preventing cardiovascular complications.
- Understanding factors influencing adherence and control in specialized care settings is vital.
Purpose of the Study:
- To identify variables associated with blood pressure control.
- To assess adherence to antihypertensive drug treatment.
- To evaluate these factors in patients within a specialized, highly complex outpatient service.
Main Methods:
- A prospective, cross-sectional study involving 253 hypertensive patients (≥18 years) at a tertiary hospital.
- Adherence assessed using the Morisky Green Levine Scale; blood pressure control defined as <140/90 mmHg.
- Multiple logistic regression analysis used to identify independent predictors (p≤0.05).
Main Results:
- Blood pressure control was achieved in 69.2% of patients; adherence was high at 90.1%.
- Independent predictors for blood pressure control included married marital status (OR 2.3), use of calcium channel blockers (OR 0.4), and number of prescribed drugs (OR 0.78).
- No variables were significantly associated with treatment adherence.
Conclusions:
- A high frequency of satisfactory adherence to antihypertensive therapy was noted.
- Blood pressure control was less prevalent and linked to social and treatment-related factors.
- Findings highlight the complexity of hypertension management beyond medication adherence.
Objective:
To evaluate and identify variables associated with the control of hypertension and adherence to antihypertensive drug treatment in a group of patients with hypertension monitored in a specialized, highly complex outpatient service.
Methods:
A prospective, cross-sectional study was carried out in the hypertension unit of a tertiary teaching hospital. Patients diagnosed with hypertensive aged 18 years and over and accompanied for at least six months were included in the study. Patients with secondary hypertension and pregnant women were excluded. The sample consisted of 253 patients. Adherence/concordance to antihypertensive treatment was assessed using the Morisky Green Levine Scale. Blood pressure control was set for values less than 140/90 mmHg. Variables with p≤0.20 in univariate analysis were included in multiple logistic regression. The level of significance adopted was p ≤0.05.
Results:
Most of patients were white, married and women, with a mean age of 65 (13.3) years old, low income, and education levels. Blood pressure control and adherence were observed in 69.2% and 90.1% of the patients, respectively. Variables that were independently associated with blood pressure control were (OR, odds ratio; CI, 95% confidence interval): married marital status (OR 2.3; CI 1.34-4.28), use of calcium channel blockers (OR 0.4; CI 0.19-0.92) and number of prescribed antihypertensive drugs (OR 0.78; CI 0.66-0.92). Adherence was not associated with any of the variables studied.
Conclusion:
There was a high frequency of patients with satisfactory adherence to antihypertensive drug treatment. Blood pressure control was less frequent and was associated with social and treatment-related factors.
More Related Videos
Related Concept Videos
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension IV: Drug Therapy and Lifestyle Modifications
Errors occurring during blood pressure monitoring
Several factors...
Blood Pressure
The average BP in an adult is typically around 120/80 mmHg (millimeters of mercury). In this measurement, the numerator (120) indicates the systolic pressure, which is the pressure in the arteries during the contraction of the heart's ventricles as blood is expelled. The denominator (80) represents the...
Hypertension and Regulation of Blood Pressure
Hypertension V: Nursing Management

