Case Report- A rare case of giant hyperplastic polyp

Area of Science:

• Gastroenterology
• Pathology

Background:

• Giant gastric hyperplastic polyps are the most frequent benign epithelial tumors of the stomach.
• They represent non-neoplastic epithelial proliferations strongly linked to inflammatory conditions such as chronic gastritis, Helicobacter pylori gastritis, and reactive gastritis.

Observation:

• A 60-year-old male presented with recurrent hematemesis, epigastric pain, nausea, and vomiting.
• The patient had no prior history of gastrointestinal bleeding, appetite loss, or significant weight reduction.

Findings:

• Diagnostic workup, including ultrasonography, upper gastrointestinal endoscopy, contrast-enhanced computed tomography, and histopathology, confirmed giant gastric hyperplastic polyps.
• These polyps result from excessive regenerative hyperplasia in chronically inflamed gastric areas and possess minimal malignant potential.

Implications:

• Giant gastric hyperplastic polyps are typically asymptomatic and incidentally discovered during endoscopy.
• Characteristic endoscopic and radiological findings, coupled with biopsy, are definitive for diagnosis and management planning.