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Bilateral ptosis/blepharitis due to lepromatous leprosy
Omar Iqbal1, Marlyn P Langford1, Ashley B Flowers2
1Department of Ophthalmology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
American Journal of Ophthalmology Case Reports
|December 17, 2021
Summary
Histopathological evaluation of eyelid tissue led to the diagnosis of lepromatous leprosy in a patient with unusual ocular inflammation. This case highlights the diagnostic value of biopsy in complex adnexal conditions.
Area of Science:
- Ophthalmology
- Dermatology
- Infectious Diseases
Background:
- Histopathological evaluation is crucial for diagnosing unusual ocular inflammation.
- Leprosy can present with varied and atypical manifestations, including ocular adnexal involvement.
Observation:
- A 51-year-old male presented with ptosis and facial edema post-eyelid cancer surgery.
- He had a history of chronic sinusitis, neuropathy, fatigue, pancytopenia, and facial changes.
- Blepharoplasty revealed granulomatous inflammation and acid-fast bacilli.
Findings:
- Histopathology confirmed lepromatous leprosy with perineural inflammation.
- The patient's symptoms improved with multi-drug therapy (MDT).
Implications:
- Blepharoplasty biopsy can be a diagnostic tool for leprosy.
- Early histopathological diagnosis is key for effective treatment of complex ocular adnexal diseases.
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