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Electronically integrated microcatheters based on self-assembling polymer films.

Boris Rivkin1, Christian Becker1, Balram Singh1

  • 1Institute for Integrative Nanosciences, Institute for Solid State and Materials Research Dresden (Leibniz IFW Dresden), 01069 Dresden, Germany.

Science Advances
|December 17, 2021
PubMed
Summary
This summary is machine-generated.

Researchers developed a self-assembled microcatheter, about 0.1 mm in diameter, integrating sensing and actuation for minimally invasive surgery. This innovation enables precise navigation and targeted liquid delivery, advancing biomedical applications.

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Area of Science:

  • Biomedical Engineering
  • Microsystems Engineering
  • Medical Devices

Background:

  • Current electronically integrated catheters require manual assembly, hindering miniaturization and integration.
  • This limitation restricts the advancement of minimally invasive surgical tools.

Purpose of the Study:

  • To report a novel, self-assembled microcatheter with embedded electronic functionalities.
  • To demonstrate the catheter's capabilities in manipulation, navigation, and targeted delivery.

Main Methods:

  • Photolithographically processed polymer thin films were used for self-assembly.
  • Electronic components for sensing and actuation were embedded into the catheter wall.
  • Functionalities were evaluated using artificial models and ex vivo tissue.

Main Results:

  • A microcatheter with a diameter of approximately 0.1 mm was successfully fabricated.
  • The catheter features actuated digits for manipulation and a magnetic sensor for navigation.
  • High-resolution magnetic tracking (below 0.1 mm) was achieved for medical tool navigation.
  • Targeted liquid delivery was demonstrated.

Conclusions:

  • The self-assembled microcatheter offers a pathway to highly flexible, microsized integrated devices.
  • This technology has the potential to expand the scope of minimally invasive surgery.
  • New biomedical applications may arise from this microcatheter technology.