Two new dammarane-type ginsenosides from Panax ginseng
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Published on: January 27, 2023
Xueni Niu1, Xiaoyu Fan1, Chongning Lv1
1School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China.
Abstract:
Two new dammarane-type ginsenosides elucidated as 3-O-[β-D-glucopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]-20-O-[α-D-glucopyranosyl-(1→4)-β-D-glucopyranosyl]-20(S)-protopanaxadiol, named Ginsenoside Rb6(2); (Z)-6-O-β-D-glucopyranosyl-dammar-20(22), 24-diene-3β, 6α, 12β-triol, named (20Z)-Ginsenoside Rh4 (4); along with five known ginsenosides(1, 3, 5, 6, 7) were isolated from the radix and rhizome of wild ginseng (Panax ginseng). The structures were determined by chemical and comprehensive spectroscopic analysis, including 1D, 2D NMR, HR-ESI-MS and hydrolysis reaction.
