Related Experiment Video
Updated: Oct 9, 2025

09:45
Author Spotlight: Studying Biomechanics of Circulating Cells by Modulating Their Electrodeformation Behavior
Published on: October 13, 2023
1.8K
Muscle Fatigue Sensor Based on Ti3 C2 Tx MXene Hydrogel
Kang Hyuck Lee1, Yi-Zhou Zhang1, Hyunho Kim1
1Physical Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Saudi Arabia.
Small Methods
|December 20, 2021
Summary
This study introduces MXene-based hydrogels (M-hydrogels) that tune electronic and ionic transport using strain and pH. These M-hydrogels function as wearable muscle fatigue sensors, offering real-time exercise monitoring via smartphone integration.
Area of Science:
- Materials Science
- Biomedical Engineering
- Nanotechnology
Background:
- MXene-based hydrogels (M-hydrogels) offer unique properties compared to conventional hydrogels.
- MXene (Ti3 C2 Tx ) integrated with polyacrylic acid/polyvinyl alcohol forms a novel M-hydrogel.
- Understanding iontronic transport modulation in M-hydrogels is crucial for advanced applications.
Purpose of the Study:
- To investigate the influence of strain and pH on the electronic and ionic transport properties of M-hydrogels.
- To develop a strain-tunable M-hydrogel for sensing applications.
- To demonstrate the potential of M-hydrogels as wearable muscle fatigue sensors.
Main Methods:
- Fabrication of MXene (Ti3 C2 Tx )-polyacrylic acid/polyvinyl alcohol hydrogel (M-hydrogel).
- Characterization of M-hydrogel's electronic and ionic transport under varying strain and pH conditions.
- Development and testing of a wearable M-hydrogel sensor coupled with a smartphone for real-time muscle fatigue monitoring.
Main Results:
- Strain application reorients MXene sheets, modulating ionic transport via surface charge pathways.
- Axial strain increases M-hydrogel's electronic resistance by disrupting the conductive MXene network.
- Iontronic characteristics are tunable by both strain and pH.
Conclusions:
- Strain and pH are effective parameters for tuning the iontronic properties of M-hydrogels.
- Developed M-hydrogel serves as a functional sensor for real-time muscle fatigue detection during exercise.
- This technology has broad potential for monitoring physiological changes in wearable devices.

