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Cutaneous pneumocystosis

C U Coulman, I Greene, R W Archibald

    Annals of Internal Medicine
    |March 1, 1987
    PubMed

    Insights

    Pneumocystis carinii, an opportunistic infection, can affect the skin in patients with acquired immunodeficiency syndrome (AIDS). Early biopsy and treatment with trimethoprim-sulfamethoxazole can lead to significant improvement.

    Area of Science:

    • Medical Mycology
    • Infectious Diseases
    • Dermatology

    Background:

    • Acquired immunodeficiency syndrome (AIDS) predisposes individuals to opportunistic infections.
    • Pneumocystis carinii is a common cause of pneumonia in immunocompromised patients.
    • Cutaneous manifestations of opportunistic infections in AIDS patients are diverse.

    Observation:

    • A 42-year-old male with AIDS presented with progressive hearing loss and bilateral external auditory canal masses.
    • Biopsy of an ear mass revealed Pneumocystis carinii.
    • The patient experienced significant reduction in ear masses after treatment.

    Findings:

    • This case represents the first report of skin involvement by Pneumocystis carinii in an AIDS patient.
    • Pneumocystis carinii otitis is a rare clinical presentation.
    • Treatment with trimethoprim and trimethoprim-sulfamethoxazole was effective.

    Implications:

    • Cutaneous lesions in AIDS patients warrant biopsy for diagnosis of opportunistic infections.
    • Early diagnosis and treatment of P. carinii skin infections can improve patient outcomes.
    • This finding expands the spectrum of P. carinii manifestations in AIDS.

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