Related Experiment Video

Updated: Oct 9, 2025

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia
08:05

Lung CT Segmentation to Identify Consolidations and Ground Glass Areas for Quantitative Assesment of SARS-CoV Pneumonia

Published on: December 19, 2020

14.4K

Incidence and characteristics of arterial thromboemboli in patients with COVID-19

Nancy Glober1, Lauren Stewart1, JangDong Seo1

  • 1Indiana University, Indianapolis, Indiana, United States.

Thrombosis Journal
|December 21, 2021
PubMed

Insights

COVID-19 infection was linked to fewer arterial thromboemboli overall, but increased risk in extremities. Metabolic syndrome predicted clot formation in COVID-19 patients.

Area of Science:

  • Cardiovascular Medicine
  • Infectious Diseases
  • Epidemiology

Background:

  • Studies indicate COVID-19 is an independent risk factor for arterial thromboemboli.
  • Arterial thromboemboli, including myocardial infarction, ischemic stroke, and peripheral artery events, are serious complications.

Purpose of the Study:

  • To determine the incidence and location of arterial thromboemboli in patients with and without COVID-19.
  • To investigate the association of comorbidities with arterial thromboemboli in the context of COVID-19 infection.

Main Methods:

  • Cross-sectional analysis of the RECOVER database (45 US medical centers).
  • Data collected on 26,974 patients, stratified by COVID-19 status.
  • Chi-squared tests used to analyze associations between comorbidities, COVID-19 status, and arterial thromboemboli.

Main Results:

  • Arterial thromboemboli incidence was 0.13% in COVID-19 positive and 0.19% in COVID-19 negative patients.
  • Arterial thromboemboli were more common in extremities than core organs in COVID-19 patients (OR 2.04).
  • Metabolic syndrome predicted core (p=0.001) and extremity (p=0.010) arterial thrombus in COVID-19 patients. Statin use was associated with lower thrombus risk (p=0.014).

Conclusions:

  • Arterial thromboemboli were less common in patients with COVID-19 than in those without.
  • Metabolic syndrome may be associated with arterial clot formation in COVID-19 patients.
Abstract

More Related Videos

In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time09:19

In Vitro Microfluidic Disease Model to Study Whole Blood-Endothelial Interactions and Blood Clot Dynamics in Real-Time

Published on: May 24, 2020

9.2K
Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses03:53

Author Spotlight: Advancements in Multiplex Detection of Respiratory Viruses

Published on: November 10, 2023

1.4K

Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
173
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
63
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
70
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
67
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
43
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
69